Back to the basics: deworming HIV-1-infected individuals

Unexplained diarrhoea in HIV-1 infected individuals

BACKGROUND Gastrointestinal symptoms, in particular diarrhoea, are common in non-treated HIV-1 infected individuals. Although various enteric pathogens have been implicated, the aetiology of diarrhoea remains unexplained in a large proportion of HIV-1 infected patients. Our aim is to identify the cause of diarrhoea for patients that remain negative in routine diagnostics. METHODS In this stud...

Getting Back to Basics

Advances in understanding basic developmental and physiological processes often have direct relevance to human disease. They provide insights into pathogenic mechanisms and reveal new pathways that can be exploited in diagnosis and the development of therapeutics.

Voting: Back to the Basics

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Back to basics in HIV prevention: focus on exposure.

Quintessence: back to basics

Quintessence is often invoked to explain the universe acceleration suggested by the type Ia supernovae observations. The aim of this letter is to demonstrate that the scalar potential necessary for quintessence is strongly constrained by the field and conservation equations. As an application, we show that all the potentials used up to now in the literature do not satisfy this constraint and so...